Professor Stephen Hughes
I am employed by Betsi Cadwaladr University Health board (BCUHB) as a Consultant Biomedical Scientist and Director of the Maelor Academic Unit of Medical and Surgical Sciences (MAUMSS). I am also affiliated with Wrexham University as a Professor of Biomedical Science.
I am a Fellow member of the Institute of Biomedical Science (IBMS), a Chartered Scientist (CSci) registered with the Science Council, and a Biomedical Scientist affiliated with the Health & Care Professions Council (HCPC).
Amongst my various external activities, I am a specialist portfolio examiner for the IBMS. This role involves assessing the suitability of hospital-based practitioners to practice at a Senior Scientist or Managerial level. I am an IBMS academic accreditation panel member at national level. This role enables me to identify and implement curriculum change to programmes at other Higher Education Institutions (HEI). I have also been Deputy Chief Examiner and member of the IBMS National Transfusion Science committee.
By invitation, I have been external examiner for Keele University (MSc Blood Sciences) and the University of Gloucester (BSc Biomedical Science), having previously performed the same role at Nottingham Trent University and the University of Wolverhampton. I am also a Fellow member of the Higher Education Academy (FHEA).
I possess a wide range of laboratory experience in the biomedical research and teaching field, and I am skilled in various immuno-haematological and biochemistry techniques. I am dedicated to maintaining high quality standards and have a passion for enhancing the student learning experience. I wish to continue to publish and increase my technical expertise, as well as advancing a professional career in academia and clinical research.
Since it's development in 2021, BCUHB-MAUMSS is the main vehicle for my current research work, which primarily involves investigating patients with benign or malignant disorders of the kidneys, bladder and prostate.
Research Interests
My current research interests are divided into the following areas:
Clinical
•Kidney stones and kidney cancer
• Benign and malignant disorders of the bladder
•Benign and malignant disorders of the prostate
•Clinical outcome measures (e.g. acute kidney injury, infection, bleeding, oedema, blood clots) and their relationship with biomarkers
Scientific
•Leukocyte biology
•Vascular endothelium
•Inflammation
•Metastasis
•Cytokines & adhesion molecules
•Novel biomarkers
Collaborators
| Name | Role | Company |
|---|---|---|
| Dr Nisreen Alwan | Academic Collaboration (BCUHB-MAUMSS and ADU) | Abu Dhabi University (ADU) |
| Professor Leandro Pecchia | Research Collaborator | University of Warwick |
| Dr Polina Prokopovich | Research Collaborator | Cardiff University |
| Prof Luis Mur | Research Collaborator | Aberystwyth University |
Publications
| Year | Publication | Type |
|---|---|---|
| 2024 | Does post-graduate surgical simulation-based education correspond to transfer of skills to real life clinical practice? A systematic review, Kumar, Bidyut;Kumar, Geeta;Roberts, Ruth;Hughes, Stephen Fôn;Payne, Joshua |
Peer Reviewed Journal |
| 2024 | A novel multilayer antimicrobial urinary catheter material with antimicrobial properties, Materials Advances . [DOI] Benjamin Gambrill;Fabrizio Pertusati;Iqbal Shergill;Stephen Hughes;Polina Prokopovich |
Peer Reviewed Journal |
| 2024 | A Novel Multilayer Antimicrobial Urinary Catheter Material with Antimicrobial Properties, [DOI] Gambrill, Benjamin;Pertusati, Fabrizio;Shergill, Iqbal;Hughes, Stephen Fôn;Prokopovich, Polina |
Peer Reviewed Journal |
| 2024 | Materials-based incidence of urinary catheter associated urinary tract infections and the causative micro-organisms: systematic review and meta-analysis, BMC Urology, 24. [DOI] Benjamin Gambrill, Fabrizio Pertusati, Stephen Fon Hughes, Iqbal Shergill & Polina Prokopovich |
Peer Reviewed Journal |
| 2024 | Can Pre-Treatment Assessment of Aqueous Vascular and Inflammatory Biomarkers In Patients with Macular Oedema Secondary to Retinal Vein Occlusion Guide Treatment Options, Archives of Clinical and Biomedical Research. [DOI] Jai Shankar;Stephen Fôn Hughes;Peter Ella-Tongwiis |
Other Journal |
| 2023 | The Use of CD200 in the Differential Diagnosis of B-Cell Lymphoproliferative Disorders, BRITISH JOURNAL OF BIOMEDICAL SCIENCE, 80. [DOI] Al-Zubaidi, Hanaan Kareem;Hughes, Stephen Fon |
Peer Reviewed Journal |
| 2023 | Should the NHS implement a screening programme for Prostate Cancer? , British International Doctors’ Association. Iqbal Shergill;Partap S. Shergill;Stephen Fôn Hughes |
Other Publication |
| 2023 | OSCAR: Omics Approaches to prostate cancer diagnosis, Journal of Endoluminal Endourology. [DOI] Tracy C Knight;Manfred Beckmann;David Rooke;Iqbal Shergill;Stephen F. Hughes;Luis AJ, Mur |
Conference Publication |
| 2022 | Selective biomarkers for inflammation and infection are associated with post-operative complications following transperineal template prostate biopsy (TTPB): a single-centre observational clinical pilot-study, [DOI] Snyper, Nana Yaa Frempomaa;Pike, Joanne;Ekwueme, Kingsley;Shergill, Iqbal;Hughes, Stephen Fôn |
Peer Reviewed Journal |
| 2022 | W018 The role of routine and novel biomarkers following flexible ureterorenoscopy for the treatment of kidney stones, Clinica Chimica Acta, 530. [DOI] C. Ellison;P. Ella-Tongwiis;S. Fon Hughes |
Peer Reviewed Journal |
| 2022 | Pre- and peri-operative clinical information, physiological observations and outcome measures following flexible ureterorenoscopy (FURS), for the treatment of kidney stones. A single-centre observational clinical pilot-study in 51 patients, BMC Urology, 22. [DOI] Stephen Fôn Hughes;Alyson Jayne Moyes,;Kevin Jones;Christopher Bell,;Abigail Duckett;Ahmed Moussa;Iqbal Shergill |
Peer Reviewed Journal |
| 2021 | Optimisation and validation of immunohistochemistry protocols for cancer research, Histology and histopathology, 36. [DOI] Ella-Tongwiis, Peter;Makanga, Alexander;Shergill, Iqbal;Hughes, Stephen Fon |
Other Publication |
| 2021 | Detection of melatonin-onset in real settings via wearable sensors and artificial intelligence. A pilot study, Biomedical Signal Processing and Control, 65. [DOI] R. Castaldo;M.J. Chappell;H. Byrne;P.F. Innominato;S. Hughes;A. Pescapè;L. Pecchia |
Peer Reviewed Journal |
| 2021 | . Prospective cohort study of induction of labor: Indications, outcome and postpartum hemorrhage., European Journal of Midwifery. [DOI] Kumar B;Kumari S;Hughes S;Savill S |
Peer Reviewed Journal |
| 2021 | Embracing Change: Learnings From Implementing Multidimensional Digital Remote Monitoring in Oncology Patients at a District General Hospital During the COVID-19 Pandemic, Clinical Cancer Informatics. [DOI] Komarzynski, Sandra;Wreglesworth, Nicholas I;Griffiths, Dawn;Pecchia, Leandro;, Subbe, Christian P;Hughes, Stephen F;Davies, Elin H;Innominato, Pasquale F. |
Peer Reviewed Journal |
| 2020 | The role of antibody expression and their association with bladder cancer recurrence: a single-centre prospective clinical-pilot study in 35 patients, BMC Urology, 20. [DOI] Ella-Tongwiis, Peter;Lamb, Rebecca May;Makanga, Alexander;Shergill, Iqbal;Hughes, Stephen Fon |
Peer Reviewed Journal |
| 2020 | Clinico-pathological Outcomes of Men with Initial Likert 2 Multiparametric Magnetic Resonance Imaging of the Prostate: Findings from a Case Series in a Non-teaching Hospital in UK, Journal of Advances in Medicine and Medical Research, 32. [DOI] Abigail Duckett;Stephen Hughes;Basharat Jameel;Mohamed Yehia;Christian Seipp;Sanjay Agarwal;Iqbal Shergill |
Peer Reviewed Journal |
| 2020 | The role of specific biomarkers, as predictors of post-operative complications following flexible ureterorenoscopy (FURS), for the treatment of kidney stones: a single-centre observational clinical pilot-study in 37 patients, BMC Urology. [DOI] Alyson Jayne Moyes;Stephen Fôn Hughes;Rebecca May Lamb;Peter Ella-tongwiis;Christopher Bell;Ahmed Moussa;Iqbal Shergill |
Peer Reviewed Journal |
| 2020 | Shock wave lithotripsy, for the treatment of kidney stones, results in changes to routine blood tests and novel biomarkers: a prospective clinical pilot-study, EUROPEAN JOURNAL OF MEDICAL RESEARCH. [DOI] Stephen F Hughes;Jones N;Thomas-Wright SJ, Banwell J;Moyes AJ;Shergill I |
Peer Reviewed Journal |
| 2020 | The Effect of Trans-urethral Resection of the Bladder Tumour (TURBT) on Routine Haematological and Biochemical Blood Tests: A Clinical-pilot Observational Study, International Journal of Biomedical Science. Hughes, S. F.;Lamb, R. M;Moyes, A;Ella-Tongwiis, P;Duckett, A;Shergill, I |
Peer Reviewed Journal |
| 2020 | The role of phagocytic leukocytes following flexible ureterenoscopy, for the treatment of kidney stones: an observational, clinical pilots-study, EUROPEAN JOURNAL OF MEDICAL RESEARCH, 25. [DOI] Stephen Fôn Hughes;Alyson Jayne Moyes;Rebecca May Lamb;Peter Ella-tongwiis;Nana Yaa Frempomaa Snyper;Iqbal Shergill |
Peer Reviewed Journal |
| 2019 | Safety and efficacy of Holmium laser enucleation of the prostate (HoLEP) in patients with previous transperineal biopsy (TPB): outcomes from a dual-centre case-control study, BMC Urology. [DOI] Chris Bell;Sacha L. Moore;Amarit Gill;Obinna Obi-Njoku;Stephen F. Hughes;Asad Saleemi;Gidon Ellis;Farooq Khan;Iqbal S. Shergill |
Peer Reviewed Journal |
| 2018 | Low power HOLEP after failed urolift: A case report using 50 Watt laser, Urology Case Reports, Urology Case Reports. [DOI] Muhammad Iqbal;Rachel Jones;Stephen Hughes;, Iqbal Shergill |
Other Publication |
| 2017 | A Mini-Review of Shock Wave Lithotripsy and Its Role in Urological Treatment of Kidney Stones, Journal of Advances in Medicine and Medical Research. Jacob A. Mear;Stephen F. Hughes;Iqbal Shergill |
Other Publication |
Professional Associations
| Association | Function | From/To |
|---|---|---|
| Science Council - Chartered Scientist (CSci) | Chartered Scientist (CSci) - (BMS:109004196) | 30/05/2008 |
| Health & Care Professions Council (HCPC) - Registered Biomedical Scientist | Registered Biomedical Scientist (HCPC number: BS41370: 1998 to Date) | 13/11/1998 |
| Institute of Biomedical Science (IBMS) - Fellow | Fellow (FIBMS: 375856) | 01/05/2008 |
| Higher Education Academy (HEA) - Fellow | Fellow of the Higher Education Academy (FHEA: 35751) | 13/11/2008 |
Honors and Awards
| Date | Title | Awarding Body |
|---|---|---|
| 09-09-2018 | Professor of Biomedical Science (0.5WTE) affiliated with Wrexham University (Faculty of Social & Life Sciences), (on-going) | Wrexham University |
Committees
| Name | From/To |
|---|---|
| Betsi Cadwaladr University Health Board (BCUHB) - Chairman of the North EAST Wales Research & Innovation Committee (on-going) | 13/11/2022 |
| Betsi Cadwaladr University Health Board (BCUHB) & Wrexham University (WU) - Chairman of the Employer Liaison Committee (on-going) | 03/09/2018 |
| North West Cancer Research (Liverpool, UK) - Research Grant Committee Member (on-going) | 01/01/2024 |
| Institute of Biomedical Science - Accreditation Panel Member (BSc & MSc Programmes), (on-going) | 13/11/2013 |
Languages
| Language | Reading | Writing | Speaking |
|---|---|---|---|
| Welsh | Native / Bilingual Proficiency | Native / Bilingual Proficiency | Native / Bilingual Proficiency |
| English | Full Professional Proficiency | Full Professional Proficiency | Full Professional Proficiency |
Other Professional Activities
| Title | From/To |
|---|---|
| University of Wolverhampton - External Examiner (BSc and MSc Biomedical Science) External Examiner |
01/09/2014 - 31/07/2017 |
| Institute of Biomedical Science: National Scientific Advisory Panel Member & Deputy Chief Examiner | 13/11/2015 - 13/11/2018 |
| Keele University - External Examiner (MSc Biomedical Science - Blood Science) | 13/11/2015 - 13/11/2018 |
| Nottingham Trent University (NTU) - External Examiner (BSc Biomedical Science & BSc Applied Biomedical Science) | 13/11/2010 - 13/11/2014 |
| Coventry University - External Expert (Consultancy) - Revalidation of the BSc Biomedical Science and BSc Applied Biomedical Science programmes (Faculty of Health and Life Sciences) | 13/01/2015 |
Consultancy & Knowledge Transfer Partnerships
| Client | Description | From/To |
|---|---|---|
| Aberystwyth University & ProTEM Services Limited | Advancing Urological Disease Diagnosis (Prostate Cancer), (on-going) | 10/11/2021 |
| Cardiff University | Materials-based incidence of urinary catheter associated urinary tract infections and the causative micro-organisms, (on-going). | 13/11/2021 - 13/11/2024 |
Journal Reviewer or Editor
| Journal Name | Activity |
|---|---|
| British Journal of Biomedical Science | Editorial Board |
| Journal of Inflammation | Peer Reviewer |
| BMC Urology | Peer Reviewer |
Outreach Activities
| Title | Description |
|---|---|
| Public Lecture - 'An innovative approach to collaborative working, staff development and promoting lifelong learning of healthcare professionals' | Professorial Public Lecture at Wrexham University (October 2024) |
| Career Pathways within the NHS | I have run dozens of workshops for students in the regional schools/colleges, promoting various career pathways within the NHS (e.g. Healthcare Sciences, Medicine, etc.). |
Teaching Interests
Haematology, Blood Sciences, Transfusion Science, Clinical Biochemistry, Research Methods
Programs/ Modules Coordinated
| Title | Subject |
|---|---|
| Professional Practice for the Biomedical & Clinical Sciences (PG) | SCI726 |
| Professional Practice for the Biomedical and Life Sciences (UG) | SCI447 |
| Blood Sciences (UG) | SCI548 |
| Biology of Disease (UG) | SCI643 |
| Blood Sciences (PG) | SCI729 |
| Advanced Laboratory Skills for the Biomedical and Life Sciences (UG) | SCI544 |